Sunday 21 April 2019

Do Statins work all the time - shocking evidence here.

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From Wickipedia
Statins - also known as HMG-CoA reductase inhibitors - are a class of lipid-lowering medications that are thought to reduce illness and mortality in those who are at high risk of cardiovascular disease.

The lipid hypothesis is that low-density lipoprotein (LDL) carriers of cholesterol are said by some to play a key role in the development of atherosclerosis and coronary heart disease. Statins are effective in lowering LDL cholesterol and widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have developed cardiovascular disease.

A recent Study, organised by the University of Nottingham, has concluded that Statins do not work for more than half of patients.  Around seven million Brits are given these 4p a day pills in order to reduce and control cholesterol levels - lowering the risk of heart disease and strokes.  But after analysing data on more than 165,000 users, researchers found that 51 per cent failed to see a significant drop in their cholesterol. These patients face a quarter higher risk of heart related death.

The study, which was published in the journal Heart, says it is unclear why so many patients are not benefiting.  Reasons may include GPs prescribing too low a dose, genetics, and patients not actually taking their medication. One in five complain that Statins cause muscle pain, leading many to ditch them.

Stains slow down the production of cholesterol by the liver. High levels contribute to stiffening and narrowing of arteries.

Professor Helen Stokes-Lampard, Chair of the Royal College of GPs, said:
"There is a substantial body of research that shows Statins are safe, effective drugs for most people when prescribed appropriately."

I guess, if you are worried at all, then seek medical advice

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